Characterization of the interaction of the regulator of G-protein signaling 10 (RGS10) and the calcium signaling protein calmodulin G-Protein Coupled Receptors (GPCRs) are of high therapeutic importance, being the targets of approximately 35% of all drugs currently in clinical use. G-Protein activation upon agonist binding to a GPCR is mediated by the exchange of GDP to GTP in the G𝛼 subunit of the heterotrimeric G-Protein, which causes the dissociation of the individual subunits (G𝛼 and the G𝛽γ dimer), initiating different signaling pathways.

There is a projection of 10 million deaths per year by 2050 due to antimicrobial resistance, highlighting the need for rapid detection and accurate identification of microorganisms. Therefore, developing fast robust diagnosis techniques will increase the recovery rates of patients suffering from various infections and will lead to significantly reduced antibiotic resistance. The membrane of bacteria contains varying lipid compositions that can be utilized as diagnostic biomarkers for disease.

Solid-state batteries offer the promise of improved energy density and safety compared to lithium-ion batteries, but degradation of materials and interfaces can play an outsized role in limiting their performance. Here, I will present our emerging understanding of the key differences between how high-capacity anode materials behave in solid-state batteries compared to in conventional liquid-electrolyte batteries.

In the quest for sustainable solutions to mitigate the environmental impact of synthetic plastic packaging, Chitosan-based films have emerged as a promising alternative. This review highlights the multifaceted attributes of Chitosan, a biopolymer derived from chitin, emphasizing its antimicrobial properties, modifiability, and biodegradability, which collectively contribute to its efficacy in packaging applications.

Porous polymers represent a class of materials wherein the arrangement of their constituent building blocks gives rise to intricate 2- or 3-dimensional porous structures. Among these, Polymers of Intrinsic Microporosity (PIMs) stand out as a distinct category characterized by their randomly contorted shapes, preventing efficient macromolecular packing in the solid state, therefore resulting in the formation of pores.

The significance of magnetic materials has grown exponentially with the technological advances achieved over the past few decades. These materials have become integral to daily life, with applications that span from decorative purposes to data storage. However, despite their abundance, magnetism remains a largely underexplored area. This lack of understanding can be attributed largely to the complexity of magnetic systems and the intricacy resulting from the myriad of factors which influence them.

The pursuit of therapeutics that can be selectively activated by radiation to enhance radiotherapy's efficacy is a pressing need. In this study, we utilized 7-Dehydrocholesterol (7DHC), a biosynthetic precursor of cholesterol, as a lipid targeted radiation-induced radiosensitizer (RIRS) for non-small cell lung cancer (NSCLC).

Over the past century, the teaching of undergraduate inorganic chemistry has experienced a roller coaster of implementation. Starting with a separation from general chemistry, to recombination, then overall neglect, inorganic chemistry content and instruction have had a dynamic influence in the world of chemical education. With curriculum changes beginning in the late 1920s, American Chemical Society (ACS) guidelines have been continually altered even into modern day.