Tags: Analytical Seminar


Properties of Surface-Active Organics in Aerosol Particles Produced from Combustion of Biomass Fuels under Simulated Prescribed-Fire and Wildfire Conditions

Surface-active organics (surfactants) have previously been measured in atmospheric aerosol particles to quantify their ability to reduce particle surface tension and influence the indirect effects of aerosol particles on the climate. However, surfactants have not been extensively studied in biomass burning aerosols (BBA), which could result in an underestimation when quantifying the contribution of surface tension on aerosol-cloud interactions.…


Pathogenic Bacteria Identification and Antimicrobial Genetics by Nanopore Sequencing

Nosocomial bacterial infections are a prevalent issue due to pathogenic bacteria having easier access to invade the bloodstream. Over the years pharmaceutical companies have released a variety of antimicrobial drugs to combat this problem, however, the over-prescription, along with bacteria’s innate ability to adapt, has led to increased resistance.1 Due to current analytical limitations, it is challenging to quickly identify pathogenic…


Using Machine Learning to Predict Ion Mobility Collisional Cross Sections

Nowadays, ion mobility is getting more and more popular due to its ability to add an additional degree of separation when coupled with traditional techniques like liquid or gas chromatography along with providing key information for a molecule’s collision crosssection (CCS). CCS is a measurement of a molecule’s effective area when it is allowed to collide with a neutral gas such as Helium or Nitrogen under the influence of an electrical current…


Quantification of C=C isomers Using Aziridine-Based Isobaric Mass Tagging

In response to environmental stress, living organisms are known to actively alter their membrane lipid compositions in their cell membranes to maintain cellular function and integrity. Glycerophospholipids, a main component of bacterial and human cell membranes, consist of a phosphate headgroup, glycerol backbone, and two fatty acids chains attached at either the sn-1 or sn-2 positions. Recent studies revealed the shift in the relative…


Literature Seminar: Alyssa Wright


Uncovering the Heterogeneity of the Human Metabolome

In recent years, significant efforts have been focused into understanding metabolic reprogramming in cancer with the hope of discerning context-specific biology that is exploitable for either for diagnosis or treatment. While some generalized phenomena such as the ‘Warburg Effect’ have been identified, the metabolic landscape of cancer is highly heterogeneous, as tumors from the same sub-type can exhibit vastly different metabolic profiles,…


Analytical Seminar: Prof. Jonathan Amster


Bridging the Academia-Industry Divide: Preparing Undergraduate Students for Roles in Chemical Industry

While there has been a recent emphasis in the field of chemistry education research on bridging the gap between research and practice, another important divide warrants attention: the growing gap between undergraduate academia and chemical industry. According to recent American Chemical Society data, approximately 70% of chemistry graduates enter industry directly after earning their bachelor’s degree. However, little is known about how these…


Charge Detection-MS: Opening a New Frontier of Mass Spectrometry

Techniques for the detection of extremely high mass ions or the analysis of heterogenous samples in mass spectrometry are often limited by overlapping charge states and poor resolution.1 The invention of electrospray ionization allowed for ionization of increasingly larger ions in mass spectrometry where multiple charging allows for the mass-to-charge ratio to be much lower than the molecular mass.2 In traditional mass spectrometry, the mass-to-…


Targeted LC–MS/MS Characterization of PFAS in Food Packaging and Their Migration into Food Simulants

Food packaging materials extensively utilize PFAS compounds for their exceptional grease and moisture resistance properties, yet their environmental persistence and potential health implications necessitate robust analytical methodologies.1 The primary analytical challenges arise from PFAS structural diversity, ultra-trace concentrations, and complex matrix interference from packaging substrates. Contemporary LC–MS/MS methodologies address these…
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