Through Thick and Thin: Chemical Strategies Towards Unique Electronic and Optical Landscapes in Atomically Precise One-Dimensional Solids

The physical properties of solids are inherently coupled to their structure and dimensionality. As such, the discovery of nascent physical phenomena and the realization of complex miniaturized devices in the solid state have incessantly relied upon the creation of stable low-dimensional crystals that approach the atomic limit.

Microneedles for Drug Delivery: Technology and Applications

Transdermal drug delivery offers an alternative to traditional oral and intravenous methods, addressing challenges like poor bioavailability and patient discomfort. However, this approach is limited to molecules with specific physicochemical properties (such as low molecular weight, high potency, and moderate lipophilicity) due to the skin’s stratum corneum barrier. Among various enhancement techniques, microneedle (MN) technology has emerged as a promising solution for delivering therapeutic agents of any size through the transdermal route.

3D Fiber Scaffolds for use in Cultivated Seafood

With a growing population comes an increase in demand for food. However, these food sources are limited by the supply and sustainability of natural resources currently available on the planet. This study introduces edible, sustainable, environmentally friendly, and consumer appealing alternative seafood production platforms. The value of 3D scaffolding over traditional 2D cell culture is explored as well as the structural optimization and scalability of 3D scaffold cultures.

Formulation of Polyhydroxyalkanoate Aqueous Dispersions for Paperboard Food Packaging

Polyhydroxyalkanoates (PHAs) have been explored for use in paperboard food and beverage packaging as an environmentally friendly replacement to petroleum-based coatings like polyethylene. Paperboard coatings are primarily extrusion coated; however, extrusion coating requires the material to be processed above its melting point. The PHB homopolymer has a polymer melting transition peak around 175° C, which also coincides with the onset of thermal degradation, making it difficult to thermally process.

The Power of Precision – Antibody Drug Conjugates in Modern Oncology

Antibody-drug conjugates (ADCs) provide a powerful approach for cancer treatment. Their precise targeting and potent cell-killing effects make them a hot topic in the development of anticancer drugs. Since the US Food and Drug Administration (FDA) approved the first ADC drug Mylotarg® (gemtuzumab ozogamicin) in 2000, 14 ADCs have been approved for marketing worldwide. Currently, more than 100 ADC candidates are in clinical trials. The chemistry behind ADC design plays a crucial role in their targeting and delivery.

Application of MoS2 in Lithium Sulfur Batteries

Lithium-ion batteries (LIBs) based on intercalation chemistry have been widely used in the past few decades. However, the overall energy density is approaching the ceiling due to the restriction of theoretical specific capacity of insertion-type oxide cathodes and graphite anodes. Lithium–sulfur (Li–S) batteries have great potential for applications in next-generation energy storage systems due to their higher theoretical capacity and energy density than LIBs. Apart from that, sulfur is earth-abundant and can be available at low prices.

Defect Management in Halide Perovskites: Enhancing γ-Ray Detector Performance through Structural, Surface, and Point Defect Control

Developing efficient, room-temperature gamma-ray detectors is crucial for medical imaging, homeland security, and nuclear safety applications. Halide perovskites have emerged as promising materials for radiation detection due to their high stopping power, defect tolerance, and cost-effective fabrication. However, the performance of perovskite-based detectors is often limited by the presence of various defects, which degrade charge collection efficiency and energy resolution.

Sustainable High-Performance Polymer Composites: Advancements in Recycling and Reprocessing

Carbon-fiber reinforced plastics (CFRP) are extensively used in aerospace and automotive industries due to their exceptional strength-to-weight ratio and corrosion resistance. With global demand for CFRP tripling between 2010 and 2020, and projected to reach 200,000 tons by 2050, managing CFRP waste is becoming increasingly critical.

Building a Higher Sensitivity Two-Dimensional Spectrometer

Ultrafast Two-Dimensional (2D) Spectroscopy is a powerful technique that has provided valuable insight into diverse systems from protein folding to isomerization of metal complexes. We aim to bring this technique to the realm of small molecules in molecular beams. 2D spectroscopy is unique because it allows for the direct measurement of coupled excitations, represented by off diagonal peaks within the spectra.

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