Tags: Organic Seminar

Photochemistry offers precise spatiotemporal control over chemical reactivity, enabling selective transformations using light as an external stimulus rather than conventional chemical reagents. In principle, such control could enable targeted drug activation, real-time imaging, and localized release of bioactive molecules while minimizing off-target effects. However, photo-medical methods are currently limited to mostly topical and subcutaneous…
Malononitrile is a readily available feedstock chemical distinguished by its high acidity and unusual electronic structure. Guided by a “Freedom of Choice” philosophy in reaction discovery, we are exploring this underutilized reagent as a platform for inventing new, often enantioselective, transformations with the potential to simplify access to sp3-rich drug-like molecules. This lecture will highlight historical milestones in malononitrile…