Calcium Nanoparticles to Stimulate Dendritic Cell and Boost T cell Immunity Against Cancer

Dendritic cells (DCs) are the most effective type of antigen-representing cells (APCs).[1] DCs capture tumor antigens, process them, and migrate to the T cell zone in tumor-draining lymph nodes (TDLNs) where they prime T cells through cross-presentation.

Structural Basis for Catalytic Diversity in the Carotenoid Oxygenase Superfamily

Carotenoid cleavage dioxygenases (CCDs) are mononuclear non-heme iron enzymes that classically split carotenoids at specific alkene bonds producing apocarotenoid products. Certain members of this enzyme superfamily have evolved to process alternative substrates with varying regio- and stereo-selectivity, and some catalyze alternative reactions including alkene geometric isomerization and ester hydrolysis.

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Spring 2022 Course Schedule

IMPORTANT: Instructor assignments for sections of General and Organic Chemistry are subject to change at any time.  This course schedule is for planning purposes only; Athena is the official source of record for available course offerings.

Please note that a single course may have multiple meeting times and locations, and be sure to factor that into your schedule planning.

Dr. Yifan Wang Joins Department of Chemistry Faculty

The Department of Chemistry welcomes Dr. Yifan Wang to the faculty as an Assistant Professor in Bioinorganic Chemistry. Dr. Wang obtained her BSc from Zhejiang Sci-Tech University (China) in 2015, and she spent Fall 2014 at the University of Liverpool (UK) as a visiting student. She then came to the States and joined Prof. Aimin Liu’s research group as a PhD student. Starting at the Georgia State University in Fall 2015, Dr. Wang relocated to the University of Texas at San Antonio with the Liu Lab in 2016 and completed her PhD study there.

Christian Freeman Named ARCS Scholar

Christian Freeman, a Ph.D. candidate in Chemistry, is among seven University of Georgia doctoral students who were recently named 2021 ARCS Scholars by the Office of Research. Recipients of the faculty-nominated award, which is given to students pursuing degrees in science, engineering, and medical research who excel in science communication, will receive $8,000 each for the next three years to support their dissertation research.



Mono-cyclopropenone Caged Dibenzocyclooctyne Triazole Derivatives: Fast-reacting, Water Soluble SPAAC Reagents

Strain-promoted azide-alkyne cycloaddition (SPAAC) has emerged as a popular click chemistry technique1. Over just the past few decades, a plethora of cycloalkyne SPAAC reagents have been developed for use as biorthogonal probes in cell and protein studies2-4, peptide stapling reagents5, and crosslinkers in polymers6. Most of these cycloalkyne reagents suffer from issues that hinder their utility; these being low aqueous solubility and slow reaction rates.

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