Confronting Pathogens with a Combination of Synthetic and Analytical Chemistry

The Manetsch laboratory focuses on synthetic chemistry and the development of LC/MS-guided medicinal chemistry approaches for the development of anti-infective agents. The first half of the seminar focuses on the streptothricin natural products class, while kinetic Target-Guided Synthesis (kTGS) is the topic of the second half of the seminar.

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Investigation On The Enzymatic Degradability Of Glycoloic Urthanes Via Fluorescence Assay

The continual rise of plastic production globally has placed a heightened focus on the end of life destination for this durable products.1 Replacing current nondegradable commodity plastics with degradable alternatives, specifically those that are compostable, can help alleviate the disposal burden that these products present.2 Through the application of a high-throughput fluorescence based enzymatic degradation screening method, we have produced a methodology for directing the synthesis of crosslinked polyuret