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Publications for: Dore, Timothy
Abate-Pella, D.; Zeliadt, N. A.; Dore, T. M.; Blank, D. A.; Wattenberg, E. V.; Distefano, M. D. Photochemical Modulation of Ras-Mediated Signal Transduction Using Caged Farnesyltransferase Inhibitors: Activation via One- and Two-Photon Excitation. ChemBioChem 2012, 13, 1009-1016.
Ma, J.; Rea, A. C.; An, H.; Ma, C.; Guan, X.; Li, M. - D.; Su, T.; Yeung, C. S.; Harris, K. T.; Zhu, Y.; Nganga, J. L.; Fedoryak, O. D.; Dore, T. M.; Phillips, D. L. Unraveling the Mechanism of the Photodeprotection Reaction of 8-Bromo- and 8-Chloro-7-hydroxyquinoline Caged Acetates. Chem.-Eur. J. 2012, 18, 6854-6865.
Dore, T. M.; Wilson, H. C. "Chromophores for the Delivery of Bioactive Molecules with Two-Photon Excitation." In: Chambers, J. J.; Kramer, R. H., eds. Photosensitive Molecules for Controlling Biological Function. New York: Humana Press; 2011:.
Ma, J.; Cheng, S. C.; An, H.; Li, M. - D.; Ma, C.; Rea, A. C.; Zhu, Y.; Nganga, J.; Dore, T. M.; Phillips, D. L. Comparison of the Absorption, Emission, and Resonance Raman Spectra of 7-Hydroxyquinoline and 8-Bromo-7-Hydroxyquinoline Caged Acetate. J. Phys. Chem. A 2011, 115, 11632-11640. Abstract
Schmidt, W. K.; Dore, T. M. "The Ras Converting Enzyme (Rce1p): Orthologs, Enzymology, and Inhibitors." In: Tamanoi, F.; Hrycyna, C. A.; Bergo, M., eds. The Enzymes. Vol. 30B. New York: Elsevier/Academic Press; 2011:.
An, H. - Y.; Ma, C.; Li, W.; Harris, K. T.; Dore, T. M.; Phillips, D. L. Resonance Raman Characterization of the Different Forms of Ground-State 8-Substituted 7-Hydroxyquinoline Cage Acetate Compounds in Aqueous Solutions. J. Phys. Chem. A 2010, 114, 2498-2505. Abstract
Pirrung, M. C.; Dore, T. M.; Zhu, Y.; Rana, V. S. Sensitized two-photon photochemical deprotection. Chem. Commun. 2010, 46, 5313-5315. Abstract
Dechert, A. - M.; MacNamara, J. P.; Breevoort, S. R.; Hildebrandt, E. R.; Hembree, N. W.; Rea, A. C.; McLain, D. E.; Porter, S. B.; Schmidt, W. K.; Dore, T. M. Modulation of the Inhibitor Properties of (Acyloxy)methyl Ketones Toward the CaaX Proteases. Bioorg. Med. Chem. 2010, 18, 6230-6237. Abstract
An, H. - Y.; Ma, C.; Nganga, J. L.; Zhu, Y.; Dore, T. M.; Phillips, D. L. Resonance Raman Characterization of Different Forms of Ground-State 8-Bromo-7-hydroxyquinoline Caged Acetate in Aqueous Solutions. J. Phys. Chem. A 2009, 113, 2831-2837. Abstract
Davis, J. M.; Kragor, C. H.; Reddie, K. G.; Wilson, H. C.; Zhu, Y.; Dore, T. M. Substituent Effects on the Sensitivity of a Quinoline Photoremovable Protecting Group to One- and Two-Photon Excitation. J. Org. Chem. 2009, 74, 1721-1729. Abstract
Porter, S. B.; Hildebrandt, E. R.; Breevoort, S. R.; Mokry, D. Z.; Dore, T. M.; Schmidt, W. K. Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy)methyl ketones. Biochim. Biophys. Acta 2007, 1773, 853-862. Abstract
Reddie, K. G.; Roberts, D. R.; Dore, T. M. Inhibition of kinesin motor proteins by adociasulfate-2. J. Med. Chem. 2006, 49, 4857-4860. Abstract
Zhu, Y.; Pavlos, C. M.; Toscano, J. P.; Dore, T. M. 8-Bromo-7-hydroxyquinoline as a Photoremovable Protecting Group for Physiological Use: Mechanism and Scope. J. Am. Chem. Soc. 2006, 128, 4267-4276. Abstract
Dore, T. M. "Multiphoton Phototriggers for Exploring Cell Physiology." In: Goeldner, M.; Givens, R. S., eds. Dynamic Studies in Biology: Phototriggers, Photoswitches, and Caged Biomolecules. Weinheim, Germany: Wiley-VCH; 2005:.
Goard, M.; Aakalu, G.; Fedoryak, O. D.; Quinonez, C.; St. Julien, J.; Poteet, S. J.; Schuman, E. M.; Dore, T. M. Light-Mediated Inhibition of Protein Synthesis. Chem. Biol. 2005, 12, 685-693. Abstract
Golde, C. M.; Dore, T. M. "The Survey of Doctoral Education and Career Preparation: The Importance of Disciplinary Contexts." In: Austin, A. E.; Wulff, D. H., eds. Paths to the Professoriate: Strategies for Enriching the Preparation of Future Faculty. San Francisco: Jossey-Bass; 2004:.
Furuta, T.; Takeuchi, H.; Isozaki, M.; Takahashi, Y.; Kanehara, M.; Sugimoto, M.; Watanabe, T.; Noguchi, K.; Dore, T. M.; Kurahashi, T.; Iwamura, M.; Tsien, R. Y. Bhc-cNMPs as either water-soluble or membrane-permeant photo-releasable cyclic nucleotides for both one and two-photon excitations. ChemBioChem 2004, 5, 1119-1128. Abstract
Dooley, C. T.; Dore, T. M.; Hanson, G. T.; Jackson, C. W.; Remington, J. S.; Tsien, R. Y. Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators. J. Biol. Chem. 2004, 279, 22284-22293. Abstract
Lu, M.; Fedoryak, O. D.; Moister, B. R.; Dore, T. M. Bhc-diol as a photolabile protecting group for aldehydes and ketones. Org. Lett. 2003, 5, 2119-2122. Abstract
Fedoryak, O. D.; Dore, T. M. Brominated hydroxyquinoline as a photolabile protecting group with sensitivity to multiphoton excitation. Org. Lett. 2002, 4, 3419-3422. Abstract
Type: 109Golde, C. M.; Dore, T. M. At Cross Purposes: What the Experiences of Today's Doctoral Students Reveal About Doctoral Education. Philadelphia, PA: The Pew Charitable Trusts; 2001.
Furuta, T.; Wang, S. S. H.; Dantzker, J. L.; Dore, T. M.; Bybee, W. J.; Callaway, E. M.; Denk, W.; Tsien, R. Y. Brominated 7-hydroxycoumarin-4-ylmethyls: photolabile protecting groups with biologically useful cross-sections for two photon photolysis. Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 1193-1200. Abstract
Wender, P. A.; Dore, T. M. A Formal Synthesis of Crinipellin B Based on the Arene-Alkene meta-Photocycloaddition Reaction. Tetrahedron Lett. 1998, 39, 8589-8592. Abstract
Wender, P. A.; Dore, T. M.; deLong, M. A. An Arene-Alkene Photocycloaddition-Radical Cyclization Cascade: The First Syntheses of cis,cis,cis,trans-[5.5.5.5]-Fenestranes. Tetrahedron Lett. 1996, 37, 7687-7690. Abstract

Timothy Dore

Adjunct Professor

B.S., University of North Carolina at Chapel Hill, 1990

Ph.D., Stanford University, 1998

Postdoctoral Associate, Howard Hughes Medical Institute, University of California, San Diego, 1998-2000