Secondary Interactions in Transition Metal Catalysis: Metal-Ligand Cooperativity and Beyond As our global population continues to grow and demand more resources, development of more advanced methods of chemical production and catalysis in an efficient manner are paramount. One such route to advancing catalysis in transition metal chemistry is to utilize not only abundant, inexpensive first-row transition metals, but also utilize more complex means of controlling chemistry around these metal centers. Type of Event: Inorganic Seminar Read more about Secondary Interactions in Transition Metal Catalysis: Metal-Ligand Cooperativity and Beyond
Hydrogen Evolution by Homoleptic Ni-Tetrathiolato Electrocatalysts In combating the global warming crisis, there is a particular interest in mitigating fossil fuel use as it remains a significant source of anthropogenic CO2 emissions. One solution for reducing fossil fuel emissions is the development of alternative fuel sources that are clean and renewable such as hydrogen gas (H2). Natural systems have evolved efficient machinery utilizing cheap, earth-abundant metals that can provide sources of alternative fuel. Type of Event: Inorganic Seminar Read more about Hydrogen Evolution by Homoleptic Ni-Tetrathiolato Electrocatalysts
The MAW Method: A Rapid Single-Phase Extraction for Bacterial Lipidomics The increasing incidence of antibiotic resistance underscores the pressing need for studies aimed at understanding its underlying mechanisms. Bacterial membrane lipids provide an avenue for studies, as they are crucial for maintaining the integrity and functionality of bacterial cell membranes. However, in-depth studies on the involvement of bacterial membrane lipids require working with numerous bacterial samples, which necessitates the need for a high-throughput lipid extraction method. Type of Event: Analytical Seminar Read more about The MAW Method: A Rapid Single-Phase Extraction for Bacterial Lipidomics
Intrinsically Disordered Proteins (IDPs): NMR Studies of IDPs Intrinsically disordered proteins (IDPs) - polypeptides that lack a defined three-dimensional structure – are commonplace in eukaryotic proteomes and often have critical impact on correct functioning of biological processes. IDPs can mediate low affinity interactions between proteins and serve as a scaffold or intermediate binding agent. Type of Event: Analytical Seminar Read more about Intrinsically Disordered Proteins (IDPs): NMR Studies of IDPs
Direct Mass Spectrometry Technologies for Intraoperative Tissue Analysis and Surgical Margin Evaluation Surgical resection remains a primary treatment for solid tumors. However, achieving tumor-free margins during surgery is challenging. Residual cancer cells at surgical margins are associated with increased recurrence and reduced survival rates. Intraoperative evaluation of surgical margins could enable more complete resection and reduce positive margins. Traditional frozen section histopathology has limitations including time-consumption, sampling errors, and availability of expertise. Type of Event: Analytical Seminar Read more about Direct Mass Spectrometry Technologies for Intraoperative Tissue Analysis and Surgical Margin Evaluation
Synthesis, Evaluation, Mechanistic Studies of Thiasugars and Their Dithia Derivatives for Application in Medicinal and Bioorganic Chemistry Thioglycosides and thiasugars both have a long history in bioorganic and medicinal chemistry 1-7 but it is widely considered that they are less “active” than the parent sugars. Type of Event: Organic Seminar Read more about Synthesis, Evaluation, Mechanistic Studies of Thiasugars and Their Dithia Derivatives for Application in Medicinal and Bioorganic Chemistry
Natural Product-Inspired Peptide Cyclization Strategies and Their Therapeutic Applications Peptide cyclization methods are useful in the development of therapeutic peptide leads with improved metabolic stability properties. To develop residue-selective peptide cyclization strategies, we draw inspiration from cyclic and lassoed peptide natural product scaffolds that exhibit diverse biological activities. Type of Event: Organic Seminar Read more about Natural Product-Inspired Peptide Cyclization Strategies and Their Therapeutic Applications
Guest Speaker: Prof. Mark Levin Type of Event: Organic Seminar Read more about Guest Speaker: Prof. Mark Levin
Asymmetric Anion-Pairing Catalysis Type of Event: Organic Seminar Read more about Asymmetric Anion-Pairing Catalysis
UGA Chemistry Hosts Open House on August 24 The Department of Chemistry will host an Open House on Thursday, August 24, from 2:30-4:00 p.m. in the breezeway between the iSTEM-1 and iSTEM-2 buildings. If you've ever considered majoring in Chemistry or adding it as a minor, or are simply curious about what UGA Chemistry has to offer, this is the event for you! Offerings at the Open House include: Read more about UGA Chemistry Hosts Open House on August 24