Chemistry
Faculty:
Richard
A. Dluhy, Ph.D.
Professor
Phone: 706-542-1950
E-mail: dluhy@chem.uga.edu
Biographical Information
Ph.D., Rutgers University, 1982
Post-Doctoral Research Scientist, National Research Council of Canada,
1982-84
Senior Research Scientist, Battelle Memorial Institute, 1984-90
University of Georgia, 1990-present
Research Interests
Our research group works in the general areas of interfacial structure and biophysical spectroscopy using physically and chemically self-assembled nanomaterials. Self-assembled nanomaterials are a class of molecules relevant to such diverse applications as opto-electronics, sensors and biomaterials. Our research interests span a range of topics related to surface and interfacial analysis in these structures. Currently, we are using interfacial vibrational spectroscopy (infrared and Raman) for the study of membrane-related phenomena such as peptide recognition and lipid-protein interactions using both in-situ and supported planar bilayer membranes. We have developed novel nanofabrication methods of substrate preparation for use in the surface-enhanced Raman (SERS) characterization of interfacial systems, and are using these methods to study molecularly-engineered surfaces for potential applications such as sensors or biomaterial coatings. We are also further developing these new SERS methods as a powerful spectroscopic sensing tool for the identification of biomedically important pathogens, including viruses and bacteria. In addition, we are interested in the development of computational methods of two-dimensional infrared correlation analysis and have developed new model-dependent 2D IR correlation methods to analyze dynamic sets of spectra.
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Publications
S.B. Chaney, S. Shanmukh, Y.-P. Zhao and R.A. Dluhy, “Randomly Aligned Silver Nanorod Arrays Produce High Sensitivity SERS Substrates”, Applied Physics Letters 2005, 87, 31908.
S. Shanmukh, L. Jones, R. Alvarez, Y.-P. Zhao, R.A. Tripp and R.A. Dluhy, “Rapid and Sensitive Detection of Respiratory Virus Molecular Signatures Using Surface Enhanced Raman Spectroscopy”, Nano Letters 2006, 6, 2630.
R.E. Sallach, M. Wei, N. Biswas, V. Conticello, S. Lecommandoux, R.A. Dluhy and E.L. Chaikof, “Size Variable Micelles Regulated by a Reversible Switch of Protein Secondary Structure”, Journal of the American Chemical Society 2006, 128, 12014.
R.A. Dluhy, S. Shanmukh and S. Morita, “Application of 2D IR Correlation Spectroscopy to Interfacial Analysis”, Surface and Interfacial Analysis 2006, 38, 1481.
N. Biswas, A.J. Waring, F.J. Walther and R.A. Dluhy, “Structure and Properties of Dimeric SP-B1-25 and SP-B8-25. IR and Raman Studies”, Biochimica et Biophysica Acta 2007, 1768, 1070.