Photosensitizer in a Molecular Bowl: Steric Protection Enhancing the Photonuclease Activity of Copper(II) Scorpionates
Photosensitizer in a Molecular Bowl: Steric Protection Enhancing the Photonuclease Activity of Copper(II) Scorpionates. Inorganic Chemistry 2005, 44, 2582-2584.
Abstract
Steric encumbrance caused by the tripodal ligand in the ternary tris(3-phenylpyrazolyl)borate copper(II) heterocyclic base complexes [Cu(B)(TpPh)](ClO4) (B = dipyridoquinoxaline, dipyridophenazine) leads to efficient cleavage of supercoiled DNA to its relaxed form upon exposure to red light at 632.8 and 694 nm as a result of protection of the photosensitizer in the mol. bowl of the {Cu(TpPh)} moiety, which generates singlet oxygen as the reactive species in a type-II process. [on SciFinder(R)]