The Development of L2X2Ru:CHR Olefin Metathesis Catalysts: An Organometallic Success Story.
A review with over 85 refs. In recent years, the olefin metathesis reaction has attracted widespread attention as a versatile C-C bond-forming method. Many new applications have become possible because of major advances in catalyst design. State-of-the-art Ru catalysts are not only highly active but also compatible with most functional groups and easy to use. This Account traces the ideas and discoveries that were instrumental in the development of these catalysts, with particular emphasis on (PCy3)2Cl2Ru:CHPh and its derivs. The discussion includes an anal. of trends in catalyst activity, a description of catalysts coordinated with N-heterocyclic carbene ligands, and an overview of ongoing work to improve the activity, stability, and selectivity of this family of L2X2Ru:CHR complexes. [on SciFinder(R)]